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PMID: 38641160 Sci Rep 2025 Oct 16;15(1):36227

Although we could not give a definitive answer to that because there was no statistically significant AE differences between group 1 and group 2, group 1 showed a numerical trend towards fewer TEAEs, fewer dropout rates due to AEs, and fewer moderate to severe AEs, suggesting that 15 mg/day dose-titration might be preferable than alternate dose titration (group 2)

Acknowledgements We thank Dr.Fuxing Dong (the Public Research Center of Xuzhou Medical University) for enthusiastic help with the laser scanning confocal microscopy experiment